Season
- Season 6 2007-01-24
- Season 5 2005-10-05
- Season 4 2004-09-28
- Season 3 2003-09-26
- Season 2 2002-10-02
- Season 1 2002-03-27
Episode
- Episode 1: George Searches For A Needle In A Haight-Stack
- Episode 2: Landlord Almighty
- Episode 3: George of the Rings
- Episode 4: Home Sweet Homeschool
- Episode 5: Leave It To Lopez
- Episode 6: Sk8r Boyz
- Episode 7: The Simple Life
- Episode 8: Trouble in Paradise
- Episode 9: E.I.? E.I. OH (aka Cold Opening)
- Episode 10: A Clear and Presentless Danger
- Episode 11: Prescription For Trouble
- Episode 12: Friends Don't Let Friends Marry Drunks
- Episode 13: George to the Third Power
- Episode 14: George Gets Assisterance
- Episode 15: Sabes Quake
- Episode 16: George Takes a Stroll Down Memory Pain
- Episode 17: George Buys a Vow
- Episode 18: George Watcha's Out For Jason
- Episode 19: George's Grand Slam
- Episode 20: George Needs Anchor Management
- Episode 21: George's Relatively Bad Idea
- Episode 22: George's Extreme Makeover: Holmes Edition
- Episode 23: George Stare-oids Down Jason
- Episode 24: George Negoti-ate It
George Lopez Season 4 George's Extreme Makeover: Holmes Edition
George raises daughter Carmen and dyslexic son Max with his wife Angie, after surviving a miserable, dysfunctional childhood at the hands of his neglectful alcoholic mother Benny.
